PLUVICTO®

PLUVICTO® is a revolutionary new treatment from Novartis for certain types of advanced prostate canter that is proven to help some men live longer and increase their quality of life.

PLUVICTO®, a cutting-edge therapy, is designed to specifically target prostate-specific membrane antigen (PSMA+) cancer cells, delivering radiation directly to them while minimizing damage to healthy tissue.

For men with metastatic castration-resistant prostate cancer previously treated with hormone therapy and chemotherapy, PLUVICTO® may be an option.

What is PLUVICTO®?

PLUVICTO® is the first and only RLT (radioligand therapy) for PSMA+ mCRPC. PLUVICTO® is not chemotherapy. RLT is a different type of radiation therapy that is injected and that targets a biomarker called PSMA, which is present on many prostate cancer cells and also some healthy cells. PLUVICTO® is designed to find and attack PSMA+ cells, including cancer cells.

If you are PSMA+, PLUVICTO® could be right for you. You can find out if you are PSMA+ by having an imaging test called a PSMA-PET scan.

What to Expect

PLUVICTO® is given in up to 6 doses. Doses are given once every 6 weeks through an intravenous (IV) injection or infusion.

While on treatment with PLUVICTO®, a team of doctors will work together to make sure you are taken care of. You will also get support from nurses and other health professionals.

Before each dose:

You will continue to have some tests done, like blood work, before and during treatment. Your first test will be performed a few days before your first dose with PLUVICTO®.
Make sure to drink plenty of water before and after each dose. This will help get rid of extra radiation in your body.

After each dose:
Your body, blood, sweat, and urine give off radiation for a while after getting PLUVICTO®. Always follow your doctor’s instructions. Also, here are some tips to help reduce overall exposure to yourself and others:

Limit close contact (less than 3 feet) with others after each dose. Stay apart longer from some higher-risk groups. Ask your doctor for more information.
Stay hydrated and urinate (pee) as much as you can.
Sleep in a separate bedroom.
No sexual activity for 7 days. Use protection after that.

Proven Results with PLUVICTO®

More Time Without Cancer Worsening

Tumors Are More Likely To Shrink

PSA Response

Understanding PLUVICTO® Side Effects

It’s normal to have concerns about side effects when starting a new treatment. Speak with your care team about any side effects you may be experiencing. You should also ask any questions you may have. The most common side effects of PLUVICTO® include: